In Brief: Using a process called biofortification, researchers at the University of Melbourne have created a genetically modified rice that produces grain with more iron and zinc.
Rice is the staple food of billions of people throughout the developing world. But beyond easing hunger pains and providing carbohydrates for energy, it has little nutritional value.
This means many people who depend on rice as a staple food are effectively being starved of essential micronutrients such as iron, zinc, and pro-vitamin A. Nutritionists call it “hidden hunger.”
Data from the World Health Organization showed that 2 billion people around the world are anaemic, in many cases due to iron deficiency. Considered as the most common and widespread nutritional disorder in the world, this condition poses a fatal health risk to pregnant women and their children.
But researchers at University of Melbourne may have found a way to alleviate iron deficiencies using—what else?—rice.
In a study published in Scientific Reports, plant geneticist Dr. Alex Johnson and his colleagues described how they were able to develop a genetically modified rice that produces high-yielding grain with significantly more iron and zinc through a process called biofortification.
“Hidden hunger isn’t a hypothetical problem, it is a real problem, and biofortification is a real solution.”
Rice grains typically contain 2-5 parts per million (ppm) of iron, and the team’s goal is to increase that to at least 13 ppm to effectively address iron-deficiencies in rice-based diets. The researchers also hoped to increase the amount of zinc from 16 ppm to 28 ppm. The best news? The team surpassed their goal, managing to get to 15 ppm of iron and 45 ppm of zinc.
“The results shows that this technology actually works in the field, not just in the glasshouse,” said Dr. Johnson, from the School of BioSciences. “We exceeded our biofortification targets and the rice was just as high yielding as existing rice varieties.”
Now, we know that genetically modified organisms are still a taboo subject. So of course, Johnson’s team tested if our bodies would readily absorb the increased quantities of iron and zinc by feeding the biofortified rice to Caco-2 cells, a human cell line that can be grown in the lab to resemble cells of the small intestine.
“There are no deal breakers in these results. We have proven our concept in a major variety of rice, and we are now ready to move this into a developing country,” said Johnson.